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Fluconazole api cas 86386-73-4 antifungal cream 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
Fluconazole api cas 86386-73-4 antifungal cream
       

  Product Specification
 
  Country  CN

 

    Product Detail
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Chemical&nbsp;Name: Fluconazole
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<p class="MsoNormal">
Fluconal-d4
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Flucostat-d4
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FluMycon-d4
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Flunazol-d4
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Flusol-d4
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<p class="MsoNormal">
Fluzon-d4
</p>
<p class="MsoNormal">
Zoltec-d4
</p>
Molecular&nbsp;Formula: C13H12F2N6O<br />
Formula&nbsp;Weight: 306.27<br />
CAS&nbsp;No.: 86386-73-4
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</p>
<p class="MsoNormal">
<img src="http://i.bosscdn.com/product/8f/cf/d0/11be82eaf4cd01ff9b257ff0ac.gif" title="86386-73-4" alt="86386-73-4" /><br />
It&nbsp;appears&nbsp;as&nbsp;white&nbsp;to&nbsp;yellow-white&nbsp;crystalline&nbsp;powder&nbsp;and&nbsp;is&nbsp;slightly&nbsp;smelly&nbsp;with&nbsp;bitter&nbsp;taste.&nbsp;It&nbsp;is&nbsp;easily&nbsp;soluble&nbsp;in&nbsp;glacial&nbsp;acetic&nbsp;acid,&nbsp;methanol&nbsp;or&nbsp;ethanol,&nbsp;hardly&nbsp;soluble&nbsp;in&nbsp;water&nbsp;and&nbsp;almost&nbsp;insoluble&nbsp;in&nbsp;ether&nbsp;with&nbsp;the&nbsp;melting&nbsp;point&nbsp;being&nbsp;137~141.6&nbsp;℃,&nbsp;or&nbsp;melting&nbsp;point&nbsp;being&nbsp;138~140&nbsp;℃&nbsp;(derived&nbsp;from&nbsp;ethyl&nbsp;acetate-hexane).<br />
This&nbsp;product&nbsp;belongs&nbsp;to&nbsp;fluorinated&nbsp;triazole&nbsp;antifungal&nbsp;drug&nbsp;with&nbsp;the&nbsp;antifungal&nbsp;spectrum&nbsp;being&nbsp;similar&nbsp;as&nbsp;ketoconazole&nbsp;but&nbsp;antifungal&nbsp;activity&nbsp;being&nbsp;higher&nbsp;than&nbsp;ketoconazole.&nbsp;Its&nbsp;mechanism&nbsp;of&nbsp;action&nbsp;is&nbsp;through&nbsp;inhibition&nbsp;of&nbsp;essential&nbsp;component&nbsp;of&nbsp;the&nbsp;fungal&nbsp;cell&nbsp;membrane,&nbsp;the&nbsp;ergosterol&nbsp;biosynthesis&nbsp;enzyme,&nbsp;blocking&nbsp;the&nbsp;ergosterol&nbsp;synthesis&nbsp;and&nbsp;breaking&nbsp;the&nbsp;integrity&nbsp;of&nbsp;the&nbsp;fungal&nbsp;cell&nbsp;wall,&nbsp;further&nbsp;inhibiting&nbsp;their&nbsp;growth&nbsp;and&nbsp;reproduction.&nbsp;Fluconazole&nbsp;oral&nbsp;tablet&nbsp;is&nbsp;available&nbsp;as&nbsp;both&nbsp;a&nbsp;generic&nbsp;and&nbsp;a&nbsp;brand-name&nbsp;drug.&nbsp;Brand&nbsp;name:&nbsp;Diflucan.<br />
Fluconazole&nbsp;comes&nbsp;as&nbsp;a&nbsp;tablet&nbsp;or&nbsp;suspension&nbsp;you&nbsp;take&nbsp;by&nbsp;mouth.&nbsp;It&nbsp;also&nbsp;comes&nbsp;in&nbsp;an&nbsp;injectable&nbsp;form&nbsp;that&nbsp;can&nbsp;only&nbsp;be&nbsp;given&nbsp;to&nbsp;you&nbsp;by&nbsp;a&nbsp;healthcare&nbsp;provider.<br />
Fluconazole&nbsp;oral&nbsp;tablet&nbsp;is&nbsp;used&nbsp;to&nbsp;prevent&nbsp;and&nbsp;treat&nbsp;candidiasis,&nbsp;a&nbsp;fungal&nbsp;infection.&nbsp;It`s&nbsp;also&nbsp;used&nbsp;to&nbsp;treat&nbsp;meningitis&nbsp;(infection&nbsp;of&nbsp;the&nbsp;brain&nbsp;or&nbsp;spinal&nbsp;cord,&nbsp;or&nbsp;both).
</p>pharmachemm.com

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