Chelerythrine->Chinese herbs

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Chelerythrine

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Chemicals->Pharmaceutical->Chinese herbs

Product Detail

Chelerythine is an alkaloidal principally obtained from the celandine, and named from the red color of its salts. It is a coloriess crystalline substance, and acts as an acrid narcotic poison. It is identical with sanguinarine.

Appearance:light-yellow or light-white powder

The major use :
1,In platelets, Chelerythrine inhibits thromboxane formation and phosphoinositide metabolism. It has an inhibitory effect on ACh-induced current in PC12 cells.
2,Chelerythrine induces apoptotic cell death in polymorphonuclear leukocyte through activation of caspase-3.6 Furthermore, Chelerythrine treated cells underwent apoptosis, with features that suggest involvement of the mitochondrial pathway, and through a mechanism that involves inhibition of the anti-apoptotic inhibitor BclXL.

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