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Xi'an Lyphar Biotech Co.,Ltd.

 
 
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Capsaicin 

  Category : Biotech->healthy food->Astragalus PE

     
Capsaicin
 
 
       

  Product Specification
 
  Model No:      ly-005
  Country  CN
  Brand  lyphar
  Weight  1 kg
  Color  white
  Packing  1 kg 1 package
  Minimum Order  1 kg
  Payment Term  TT,Western Union
  cas  404-86-4

 

    Product Detail
  Product Name: Capsaicin

CAS #: 404-86-4

Molecular formula: C18H27NO3

Molecular weight: 305.41

Formulation: Off white powder

Purity: 10%-99%

Function:

Capsaicin is a natural compound with pharmacological and toxicological effects, which given its hydrophobicity, can influence the structure of membranes. The interaction of capsaicin with model membranes of dipalmitoylphosphatidylcholine and dielaidoylphosphatidylethanolamine has been studied by using differential scanning calorimetry, fluorescent probe spectroscopy and 31P-nuclear magnetic resonance. Capsaicin remarkably affects the phase transition of dipalmitoylphosphatidylcholine, shifting the transition temperature to lower values, and giving rise, at relatively high capsaicin concentrations, to the appearance of two peaks in the thermogram. These peaks may correspond to separated phases as indicated by the partial phase diagram. Whereas capsaicin did not affect the fluorescence polarization of the probes diphenylhexatriene and trimethylammonium-diphenylhexatriene, it clearly affected that of the probe 2-anthroyloxystearic acid, indicating that the perturbation produced by capsaicin on the membrane would be mainly at the position where this fluorophore is located. On the other hand, capsaicin, at relatively low concentrations, gives rise to immiscible phases in the presence of dielaidoylphosphatidylethanolamine and decrease the temperature of the lamellar to hexagonal HII phase transition. At concentrations of capsaicin higher than 0.3 mol fraction, isotropic phases were detected. The possible implications of the effects of capsaicin on biological membranes are discussed.

   


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